A functional variant in the UBE2B gene promoter is associated with idiopathic azoospermia
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چکیده
منابع مشابه
A functional variant in the UBE2B gene promoter is associated with idiopathic azoospermia
BACKGROUND A variety of genetic variants lead to abnormal human spermatogenesis. The ubiquitin-conjugating enzyme E2B (UBE2B) plays a significant role in spermatogenesis as Ube2b-knockout male mice are infertile. METHODS In this study, we sequenced the exon and promoter region of UBE2B in 776 patients diagnosed with idiopathic azoospermia (IA) and 709 proven fertile men to examine whether UBE...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2015
ISSN: 1477-7827
DOI: 10.1186/s12958-015-0074-4